The artist has handed over the complete sum of his £25,000 Mercury Prize cash to the MVT, which works to save the Britain's small concert spaces.
Fender was given the award on October 16 as his new release his work was named the top album of the past year.
The musician has decided to donate the funds to the trust, in appreciation of the vital role small stages fulfilled in his initial steps.
"I personally would not have achieved my current career if it hadn't been for all the shows I played around the North East, and beyond, when I was just getting going," remarked Sam Fender. "These locations are renowned, but they are facing challenges."
Beginning in 2023, more than 150 of these spaces have permanently closed – roughly one-sixth of the total UK scene.
In the last year, major artists like the band Pulp, Coldplay, Katy Perry and Sheeran have all aided the trust in its initiatives to support the industry, by adding a small levy to their ticket prices, which benefits independent venues.
Sam Fender also joined in, collecting in excess of £100,000 on his recent tour to help numerous small stages across the UK.
The donation assisted venues that were confronting possible closure due to difficulties stemming from floods, blazes and family tragedies, as well as regulatory hurdles, court cases and neighbor objections.
Some locations obtained financial assistance in upgrading amenities and sound and lighting systems that positively impacted musicians and concertgoers.
"The concept that revenue from performances in large arenas helps the independent spots, where it all starts for performers like me, is just common sense," Sam Fender has commented.
Fender is far from the only musician to give his Mercury Prize winnings to charitable organizations.
Back when the band won the award in the mid-90s for their album their work, lead singer Cocker stated that the act would give their winnings to the charity War Child.
That year, musician she split her award between a few good causes, like the children's charity and a Sickle Cell charity.
"Additionally, I gave a grand to the center, to their gymnastics program, because I trained in gymnastics when I was growing up and they lacked updated gear," the artist told the media.
Previously, the band gave their funds to the community center that supported their group, in addition to other local music groups.
And winners that year M People contributed their winnings to a multiple sclerosis charity after a close contact was found to have the condition.
"The victory was sufficient," said artist Small. "The cash was the extra but we could do without the cherry, because we had the main prize. So our success affected the lives of others."
Recently, the trust shared it had saved a couple of local spots in the South East, by transferring them to community ownership.
The Joiners in Southampton and the second in Bristol were bought under the Own Our Venues scheme, which is supported by the arts council and music fans who acquire "stakes" in the buildings.